Draft Toxicological Profile for Wood Creosote, Coal Tar Creosote, Coal Tar, Coal Tar Pitch, and Coal Tar Pitch VolatilesU.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, 2000 - 342 ページ |
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1-hydroxypyrene animals anthracene ATSDR beechwood creosote benzo[a]pyrene biological biomarker body weight cancer carcinogenic chemical coal tar aerosol coal tar creosote coal tar pitch coal tar products compounds concentrations contaminated controls creosote bush creosote components creosote constituents creosote-contaminated creosote-derived creosote-treated cresol Culp decrease dermal exposure detected DNA adducts dose Environmental Protection Agency excretion exposure to coal exposure to creosote female fluorene fractions genotoxicity gestational days groundwater hazardous waste sites HEALTH EFFECTS HUMAN EXPOSURE increased ingestion inhalation exposure isomer levels liver LOAEL lung male manufactured gas plant metabolism metabolites mg/kg mg/m³ mixture Miyazato Mouse mutagenic naphthalene NIOSH NOAEL observed oral exposure PAH components PAHs patients phenanthrene phenol pitch volatiles plant polycyclic aromatic hydrocarbons POTENTIAL FOR HUMAN psoriasis pyrene rats exposed reported respiratory risk sediment significantly skin soil Springer substances tissue toxicity Toxicol tumors U.S. Environmental Protection urinary weeks Weyand wood creosote wood preservative wood treatment