Molecular infection biology: interactions between microorganisms and cells
Wiley-Liss, 2002/10/03 - 339 ページ
This comprehensive volume focuses on molecular methods and principles of prokaryotic and eukaryotic pathogens. The authors present the molecular and cellular aspects by focusing on the interactions between pathogenic microorganisms and their hosts. The publication begins with an overview of the most important and dangerous causative agents of infectious diseases. Next are discussions of how microbial "weapons," pathogenicity factors, protein secretion machines, and surface variation systems work, presenting the molecular and genetic methods that are used by scientists for their discovery and analysis. Furthermore, infectious diseases are discussed in light of the newly formed research areas of evolutionary and cellular microbiology and genomics. Future aspects on diagnostic techniques, therapy, and vaccine development are also presented.
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acid actin activation adhesins aeruginosa albicans antibiotics antibodies antigen apoptosis bacteria binding biofilms capsule cause Chapter cholerae chromosome coding colonization cytoplasmic disease effector encoding enzymes epithelial cells Escherichia coli eukaryotic example fimbriae formation function gene expression genetic genome gonorrhoeae gram-negative Hacker Helicobacter pylori horizontal gene transfer host cells human hybridization identified immune response immune system induce infection biology inhibit integrins interaction intestinal intracellular invasin invasion kinase Legionella Listeria lymphocytes macrophages mechanisms microbial microorganisms molecular molecules mRNA mutants Neisseria operon organisms pathogenic bacteria pathogenic microorganisms pathogenicity factors pathogenicity islands pathway pertussis phage phase variation plasmid pneumoniae produced protease proteins pyogenes receptors recombination region regulator resistance Salmonella secretion system Shiga toxin Shigella siderophores specific strains Streptococcus structures subunit surface synthesis Table target toxin tract transcription translocated transposon Trends Microbiol typhimurium vaccines variants Vibrio Vibrio cholerae virulence factors virulence genes virus viruses vivo Yersinia