Goodman and Gilman's The Pharmacological Basis of TherapeuticsMacmillan, 1980 - 1843 ページ **** A classic text, now in its 50th year, recommended as a first purchase by Brandon-Hill. The new edition reflects the impact of modern biology since the previous edition in 1985: novel drugs produced by recombinant DNA technology, detailed knowledge of the structure and function of dozens of receptors, major progress in rational drug design, and improved treatment from appreciation of the importance of interplay between pharmacodynamics and pharmacokinetics. Annotation copyrighted by Book News, Inc., Portland, OR |
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absorption acid action activity acute administration adrenergic agonists alcohol alkaloids amines anesthesia Anesthesiology anesthetic anti-ChE agents antidepressants antipsychotic antipsychotic drugs arterial atropine autonomic B-adrenergic barbiturates benzodiazepines blockade blocking agents blood flow blood pressure brain carbon dioxide cardiac cardiovascular catecholamines cause cells central Chapter chlorpromazine cholinergic chronic clinical compounds concentration decrease depression diazepam disease dopamine dosage doses enflurane enzyme epinephrine excreted fibers function ganglia ganglionic gastrointestinal guanethidine halothane hepatic Hydrochloride hypotension increase inhalation inhibition inhibitors injection interaction intravenous isoproterenol levodopa lithium local anesthetics mechanism membrane metabolism metabolites morphine muscarinic nephrine nerve nervous system neuromuscular neurons nicotine nitrous oxide norepinephrine occur opioids oral oxygen patients peripheral Pharmacol pharmacological phenobarbital phenothiazines phenytoin Physiol plasma potential produce propranolol receptors release renal reserpine respiratory response result seizures side effects skeletal muscle sleep smooth muscle spinal stimulation sympathetic sympathomimetic synaptic Ther therapeutic therapy tion tissues toxicity transmitter treatment tricyclic usually