Toxicological Profile for Benzene: Draft

absorption Aksoy ambient ANALYTICAL METHODS anemia animal studies aplastic anemia benzene concentrations benzene exposure benzene levels benzene metabolites benzene toxicity biomarkers blood bone marrow cancer carcinogenicity catechol cells chemical Chromosomal aberrations chronic concentrations of benzene contaminated cytochrome P-450 decreased dermal exposure detection dose drinking water effects of benzene Environ Health Environmental Protection Agency epidemiological estimated ethanol excretion exposure levels exposure to benzene gasoline GC/FID GC/MS genotoxic glucuronide groundwater hazardous waste hazardous waste sites HEALTH EFFECTS hematotoxicity HSDB HUMAN EXPOSURE hydroquinone industrial leukemia leukopenia levels of benzene liver LOAEL lymphocytes metabolism metabolism of benzene metabolites mg/kg mg/kg/day mg/L Micronuclei Micronuclei increase Mouse bone marrow Mutat NIOSH NOAEL oral exposure organic OSHA pancytopenia phenol ppm benzene rats reported risk route Sabourin sample Sister chromatid exchange skin smoke Snyder soil solvents sulfate thermally desorb tissues toluene Toxicology U.S. Environmental Protection urinary phenol urine vitro workers exposed