Toxicological Profile for Polycyclic Aromatic Hydrocarbons

1-hydroxypyrene absorption acenaphthene activity administration ANALYTICAL METHODS animals anthracene Applicable to Polycyclic Aquatic Aromatic Hydrocarbons continued benz[a]anthracene benzo[a]pyrene benzo[a]pyrene-induced benzo[b]fluoranthene benzo[g,h,i]perylene Cancer Res Carcinogenesis carcinogenic CELDS cells Chem chemical chrysene coal coal tar compounds contaminated data No data dermal exposure detected dibenz[a,h]anthracene diol DNA adducts DNA damage dose Environ Environmental Protection Agency enzymes epoxide evaluated excretion exposed exposure to PAHs fluoranthene fluorene gavage Gene mutation genotoxic hamster hazardous waste HEALTH EFFECTS HUMAN EXPOSURE increased induced inhalation intermediate-duration intratracheal levels liver LOAEL lung metabolism metabolites mg/kg mg/kg/day mg/L mg/m³ mice microsomes mixtures mutagenic Mutat Res ng/m³ organic PAH concentrations PAHs particles phenanthrene Polycyclic Aromatic Hydrocarbons polynuclear aromatic hydrocarbons POTENTIAL FOR HUMAN pyrene rats REGULATIONS AND ADVISORIES samples sediments Sister chromatid exchange smoke soil studies tissues total PAH toxicity Toxicol Transformation No data tumors typhimurium U.S. Environmental Protection urine vitro Weyand Yes Yes Yes µg/kg µg/L µg/m³