ToxicologyHans Marquardt, Siegfried G. Schäfer, Roger O. McClellan, Frank Welsch Academic Press, 1999/10/05 - 1330 ページ Toxicology is a comprehensive text for researchers and graduate students in toxicology and public health. It addresses every aspect of the field, starting with the fundamentals and incorporating such areas as organ toxicology, applications, and environmental toxicology. In addition to covering the traditional subject matter of toxicology, special emphasis has been placed on recent areas of interest, such as risk assessment, apoptosis, and methodical developments. Key Features * Comprehensive text, covering all aspects of the field of toxicology * Analyzes the importance of toxicokinetics and metabolism as well as cellular targets for the mechanisms of toxic effects * Identifies the various classes of chemical compounds responsible for the toxic effects * Describes the approaches and methods used by various disciplines which investigate toxic effects and their prevention * Adapted from a very successful German text, this edition is completely revised and expanded * The text is well illustrated with diagrams, charts, and tables |
目次
| 1 | |
| 9 | |
ORGAN TOXICITY | 271 |
TOXICOLOGY OF COMPOUNDS | 601 |
APPLICATIONS OF TOXICOLOGY | 1025 |
RISK ASSESSMENT | 1151 |
APPENDIX | 1199 |
| 1231 | |
多く使われている語句
absorption acid action activity acute agents alcohol animals antigen apoptosis benzene binding blood cancer carcinogenesis carcinogens cause cell death cellular chemical chronic clearance complex compounds concentration cytochrome P450 cytokines cytotoxic damage decrease detected disease dose drug effects enzymes epoxide estrogen ethanol example excreted experimental exposure factors formation function gene genetic genotoxic glomerular glutathione half-life hormones humans hydrocarbons immune system increased induced inhalation inhibition initiated interaction intestinal kidney kinetics lead lesions levels lipid liver lung lymphocytes malformations mechanisms membrane metabolism metabolites mg/kg mg/m³ mice mixtures molecules mutagenic mutation necrosis nephrotoxicity normal organ oxidative oxygen pathway peroxide plasma polycyclic aromatic hydrocarbons potential processes produce proliferation protein radicals rats reactions reactive receptor renal response risk assessment rodents role skin specific studies substances substrate T-cells Table target teratogenic thalidomide thyroid tion tissue toxic Toxicol toxicology toxins transgenic tubular tumor promoters vitro vivo xenobiotics