Diabetes Mellitus: A Fundamental and Clinical TextDerek LeRoith, Simeon I. Taylor, Jerrold M. Olefsky Lippincott Williams & Wilkins, 2004 - 1540 ページ Thoroughly revised and updated, this Third Edition encompasses the most recent advances in molecular and cellular research and describes the newest therapeutic modalities for type 1 and type 2 diabetes mellitus. Chapters by leading experts integrate the latest basic science and clinical research on diabetes mellitus and its complications. The text is divided into ten major sections, including extensive sections on therapeutics, diabetes during pregnancy, and complications. New chapters cover stem cell therapy for type 1 diabetes; genetics and treatment of obesity; new therapies to promote insulin action; vasculopathy; islet cell protocols; triglycerides in muscle; hypoglycemia in the adult; and the Diabetes Prevention Program. |
目次
80 | 10 |
Processing of the Insulin Molecule | 27 |
Electrophysiology of the Pancreatic BCell | 51 |
Sulfonylurea Receptors Adenosine Triphosphate | 69 |
Insulinotropic GlucagonLike Peptides | 99 |
on the Pancreatic BCell | 115 |
Effects of Insulin on the Control of Blood | 183 |
Insulin Signaling and Metabolic Regulation | 207 |
Surrogate Bcells for Insulin Replacement | 763 |
Stem Cells 773 67 Triglyceride in Muscle | 987 |
and Marvin C Gershengorn 68 Candidate Genes for Type 2 Diabetes | 1003 |
Genetic Syndromes Associated with Severe Insulin | 1015 |
Noninvasive Imaging of Insulin Action and for Genetic Studies of Diabetes Mellitus | 1029 |
Genetics of Human Obesity 827 Diabetes Mellitus | 1041 |
Treatment 839 72 Primate Animal Models of Type 2 Diabetes | 1059 |
The Diabetes | 1077 |
The Insulin Signaling Network and Insulin | 225 |
of Diabetes Mellitus | 245 |
Regulation of Insulin Action by ProteinTyrosine | 255 |
Small GTPases and SerineThreonine Protein | 269 |
Protein Kinase C | 301 |
Regulation of Glycogen Synthesis | 317 |
Cellular and Molecular Processes Regulating | 349 |
Control of Lipolysis in Adipocytes | 365 |
of Lipolysis and Insulin Secretion | 373 |
Gene Regulation | 383 |
Insulin Degradation | 413 |
Insulin and the RasDependent Signaling | 421 |
Germline Manipulation of Glucose Transport | 431 |
ProliferatorActivated Receptory | 441 |
30 | 457 |
Diabetes Mellitus | 471 |
37 | 559 |
Animal Models of Autoimmune Diabetes | 591 |
Insights from Transgenic and Gene Targeting | 611 |
Diabetic Ketoacidosis and the Hyperglycemic | 627 |
THERAPEUTICS FOR TYPE 1 | 643 |
Exercise for the Patient with Type 1 Diabetes | 671 |
Insulin Therapy and Home Monitoring for Type I | 683 |
Immune Intervention | 701 |
Genetics of Type 1 Diabetes 483 | 712 |
Roles of CellMediated Immunity | 734 |
Major Histocompatibility Locus and Other Genes | 744 |
Program Research Group | 1085 |
Glucose Transporters and Pathophysiologic Livia S A Augustin and Cyril W C Kendall | 1099 |
Effect of Chronic 76 Insulin Secretogogues Sulfonylureas Meglitinides | 1107 |
Inflammation Tumor Necrosis Factora | 1123 |
Regulators of Metabolic Integration 78 Peroxisome proliferatorActivated Receptor | 1139 |
Fatty Acids and Insulin Resistance 979 Diabetes | 1151 |
Glinides | 1163 |
81 | 1171 |
Mellitus | 1177 |
Intensive Insulin Therapy for Patients with Type 2 | 1191 |
Pathophysiology of Hypertension | 1208 |
84 | 1225 |
Effects of Maternal Diabetes Mellitus | 1251 |
Pregnancy and Complications of Diabetes | 1265 |
88 | 1274 |
DESCRIPTIVE | 1301 |
Pathogenesis of Diabetic Nephropathy | 1315 |
An Overview of Clinical | 1331 |
Hypoglycemia in the Adult | 1427 |
OF COMPLICATIONS | 1439 |
Hyperinsulinemia and Insulin Resistance | 1457 |
The Role of Growth Factors in the Pathogenesis | 1469 |
Complications | 1485 |
Diabetic Vasculopathy | 1503 |
| 1513 | |
他の版 - すべて表示
多く使われている語句
3T3-L1 adipocytes Acad Sci USA activation adipocytes adipose tissue amino acids B-cell beta-cell binding Biochem Biol Chem biosynthesis Ca2+ Clin Invest decrease domain effect of insulin Endocrinol Endocrinology enzyme exocytosis fatty acids FKHR function gene expression gene transcription glucagon glucose transport glucose uptake GLUT4 glycogen synthase granules hormone human hypoglycemia increase inhibition inhibitors insulin action insulin gene insulin receptor insulin release insulin resistance insulin response insulin secretion insulin signaling insulin-stimulated interaction intracellular IRS proteins islet amyloid isoforms KATP KATP channels lipid liver mechanism mediated metabolism mice Mol Cell Biol molecular motif mRNA mutations Natl Acad Sci obesity overexpression pancreatic islets PDK1 peptide phos phosphatase phosphorylation Physiol PI 3-kinase plasma membrane Proc Natl Acad proinsulin promoter protein kinase PTP1B rat adipocytes regulation role secretory sequence skeletal muscle stimulation substrate subunit sulfonylurea sulin synthesis target tion transcription factor type 2 diabetes tyrosine vesicles vitro vivo