Handbook of NeuroendocrinologyGeorge Fink, Donald W. Pfaff, Jon Levine Academic Press, 2011/08/31 - 894 ページ Neuroendocrinology, the discipline concerned with how the nervous system controls hormonal secretion and how hormones control the brain, is pivotal to physiology and medicine. Neuroendocrinology has disclosed and underpins fundamental physiological, molecular biological and genetic principles such as the regulation of gene transcription and translation, the mechanisms of chemical neurotransmission and intracellular and systemic feedback control systems. Reproduction, growth, stress, aggression, metabolism, birth, feeding and drinking and blood pressure are some of the bodily functions that are triggered and/or controlled by neuroendocrine systems. In turn, neuroendocrine dysfunction due to genetic or other deficits can lead, for example, to infertility, impotence, precocious or delayed puberty, defective or excessive growth, obesity and anorexia, Cushing’s Syndrome, hypertension or thyroid disorders. These as well as neuroendocrine tumors are some of the themes covered in the 36 chapters of the Handbook. Drafted by internationally acknowledged experts in the field, the Handbook chapters feature detailed up-to-date bibliographies as well as "how do we know?" call out sections that highlight the experimental or technical foundations for major concepts, principles, or methodological advances in each area. Aimed at senior undergraduate and graduate students, post-doctoral fellows and faculty in neuroscience, medicine, endocrinology, psychiatry, psychology and cognate disciplines, the Handbook of Neuroendocrinology satisfies an unmet need that will prove useful at the laboratory bench as well as in the office.
|
この書籍内から
検索結果1-5 / 87
... Cortisol Awakening Response 58 Glucocorticoid Negative Feedback Control in the HPA: Interactions with Neural Circuits 59 Interaction Between Negative Feedback and Circadian Rhythm in the Hypothalamice PituitaryeAdrenal (HPA) System 60 ...
... cortisol or corticosterone, moderate ACTH synthesis and release (efferent limb). Allostasis e that is, change in HPA activity to cope with increased stress load e is thought to be brought about by change in feedback set-point ...
... (cortisol in the human and corticosterone in rodents), the same mechanisms are involved in allostasis, which is brought about by a change in set point presumed to enable the organism to anticipate and deal with the physiological ...
... Cortisol Awakening Response In man, waking is closely associated with a cortisol awakening response (CAR) which typically involves an increase in salivary cortisol concentrations peaking around 30 minutes after waking.20 The CAR has ...
... CORTISOL ACTH PVN (–) CRF(+)AVP(+) ANP(–) STRESS BRAIN PIT CYT IDS ACTH (+) ADRENAL (–) CORTISOL hipp FIGURE 3.4 Schematic diagram of the elements involved in glucocorticoid negative feedback. The paraventricular nucleus (PVN) contains ...
目次
1 | |
95 | |
Part III Hormones Brain Function and Behavior | 329 |
Part IV Neuroendocrine Pathology | 595 |
Subject Index | 791 |
Author Index | 803 |