Perilla: The Genus Perilla
Perilla includes review articles describing the cultivation, traditional and modern applications, the chemical, pharmacological, medical and clinical studies of this plant and its active compounds. The cell culture of Perilla, the genetic control of the plant, and the isolation and structural elucidation of a number of its active compounds such as terpenoids, phenolics, glycosides, flavonoids and anthocyanins are discussed. Also reflected is the use of Perilla seed oil, containing a high degree of a-linolenic acid (n-3 fatty acid) an essential fatty acid in human nutrition and beneficial in the treatment of disease. Special focus is given to the recent development in the preparation and application of Perilla leaf extract for the treatment of allergies. This comprehensive treatment of Perilla should be of interest to everyone involved in medicinal and aromatic plant research.
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2 CULTIVATION OF PERILLA
3 CELL AND TISSUE CULTURES OF PERILLA
4 APPLICATIONS AND PRESCRIPTIONS OF PERILLA IN TRADITIONAL CHINESE MEDICINE
5 ANTIINFLAMMATORY AND ANTIALLERGIC ACTIVITIES OF PERILLA EXTRACTS
6 PERILLA AND THE TREATMENT OF ALLERGY A REVIEW
7 A CLINICAL INVESTIGATION OF PERILLA EXTRACT CREAM FOR ATOPIC DERMATITIS
8 THE DEVELOPMENT AND APPLICATION OF PERILLA EXTRACT AS AN ANTIALLERGIC SUBSTANCE
9 LIPID COMPOSITION AND NUTRITIONAL AND PHYSIOLOGICAL ROLES OF PERILLA SEED AND ITS OIL
10 CHEMICAL STUDIES ON THE CONSTITUENTS OF PERILLA FRUTESCENS
11 CHEMOTYPES AND PHARMACOLOGICAL ACTIVITIES OF PERILLA
12 MOLECULAR BIOLOGY IN PERILLA FRUTESCENS Isolation of Specifically Expressed Genes in Chemotypes
13 THE CHEMISTRY AND APPLICATIONS OF ANTHOCYANINS AND FLAVONES FROM PERILLA LEAVES
14 ANTHOCYANINS FROM PERILLA
activity of Perilla acuta allergen allergy anthocyanin content anthocyanin production anthocyanins and flavones antiallergic antioxidative application of Perilla ascorbic acid asthma atopic dermatitis bioreactor biosynthesis Britt caffeic acid callus cancer cell cultures Chem chemical chemotypes China Chinese herb clinical components composition compounds concentration constituents containing crispa cultivation cultures of Perilla diet dietary dillapiole diseases effect of Perilla essential oil Figure flavones flavonoids formation formula frutescens cells Fujita genes Genetic glucosides Group growth herbal Honda increased isolated Japan Japanese Koezuka Korean Kosuna light irradiation lipids malonylshisonin membrane mice monoterpene monoterpenoid O-linolenic acid patients Perilla anthocyanins Perilla extract Perilla frutescens Perilla leaf extract Perilla oil Perilla seed oil perillaldehyde perillosides phenylpropanoids Phytochemistry pigment protein purple Perilla rats reported rhinitis rosmarinic acid shisonin solution sterol studies symptoms Tabata Table temperature TNF production traditional Chinese medicine treatment of allergy tumor volatile Yamazaki Yoshida Zarshi Zhong
vii ページ - Such methods as in vitro fertilisation, meristem cultures and somatic embryogenesis are used. The transfer of sections of DNA is giving rise to controversy in the case of some end-uses of the plant material. Some suppliers of plant raw material are now able to certify that they are supplying organically-farmed medicinal plants, herbs and spices. The Economic Union directive (CVO/EU No 2092/91) details the specifications for the obligatory quality controls to be carried out at all stages of production...
vii ページ - PREFACE TO THE SERIES There is increasing interest in industry, academia and the health sciences in medicinal and aromatic plants. In passing from plant production to the eventual product used by the public, many sciences are involved. This series brings together information which is currently scattered through an ever increasing number of journals.
ii ページ - ... of industrial importance. Edited by Dr Roland Hardman Volume 1 Valerian, edited by Peter J. Houghton Volume 2 Perilla, edited by He-ci Yu, Kenichi Kosuna and Megumi Haga Volume 3 Poppy, edited by Jeno Bernath Volume 4 Cannabis, edited by David T.
ii ページ - The publisher will accept continuation orders which may be cancelled at any time and which provide for automatic billing and shipping of each title in the series upon publication.
vii ページ - The plant raw materials are roots, rhizomes, bulbs, leaves, stems, barks, wood, flowers, fruits and seeds. These yield gums, resins, essential (volatile) oils, fixed oils, waxes, juices, extracts and spices for medicinal and aromatic purposes. All these commodities are traded world-wide. A dealer's market report for an item may say "Drought in the country of origin has forced up prices". Natural products do not mean safe products and account of this has to be taken by the above industries, which...
vii ページ - This series brings together information which is currently scattered through an ever increasing number of journals. Each volume gives an in-depth look at one plant genus, about which an area specialist has assembled information ranging from the production of the plant to market trends and quality control. Many industries are involved such as forestry, agriculture, chemical, food, flavour, beverage, pharmaceutical, cosmetic and fragrance.
viii ページ - Medicine and this office in 1994 assisted the filing of several Investigational New Drug (IND) applications, required for clinical trials of some Chinese herbal preparations. The significance of these applications was that each Chinese preparation involved several plants and yet was handled as a single IND. A demonstration of the contribution of efficacy, of each ingredient of each plant, was not required.
viii ページ - Asia. A similar situation exists in Africa and South America. Thus, a very high percentage of the world's population relies on medicinal and aromatic plants for their medicine. Western medicine is also responding. Already in Germany all medical practitioners have to pass an examination in phytotherapy before being allowed to practice. It is noticeable that throughout Europe and the USA, medical, pharmacy and health related schools are increasingly offering training in phytotherapy.
viii ページ - The high costs of such ventures and the endless competition from 'me too' compounds from rival companies often discourage the attempt. Independent phytomedicine companies have been very strong in Germany. However, by the end of 1995, eleven (almost all) had been acquired by the multinational pharmaceutical firms, acknowledging the lay public's growing demand for phytomedicines in the Western World. The business of dietary supplements in the Western World has expanded from the health store to the...
vii ページ - Natural products do not mean safe products and account of this has to be taken by the above industries, which are subject to regulation. For example, a number of plants which are approved for use in medicine must not be used in cosmetic products. The assessment of safe to use starts with the harvested plant material which has to comply with an official monograph. This may require absence of, or prescribed limits of, radioactive material, heavy metals, aflatoxin, pesticide residue, as well as the...