Biological Interactions Of Sulfur CompoundsStephen C. Mitchell CRC Press, 2003/09/02 - 225 ページ This text focuses on the biological interactions of sulphur compounds which arise specifically from the presence of the sulphur atom within the molecule. The book opens with introductory chapters on the chemistry and biology of sulphur, before tackling the field by introducing compounds which share a common chemical combination. In general, following a description of the uses and impact upon the biological field, specific chemical group characteristics are discussed together with the biological activity and structure-activity relationships where known. The toxicity of such compounds, their consequences in biochemical and clinical terms, and their mechanisms of biological interaction are then addressed. |
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action activity addition AdoMet agents American Chemical Society amino acids analogues animals appears atom bacteria binding Biochemical Biochemistry biological carbon cause cell Chemical Chemistry Clinical complex compounds concentrations conjugates containing converted cyclamate cysteine derivatives disease disulfide disulfide bonds dose drug effects electron enzyme esters et al excreted Experimental Figure formation function give glutathione human hydrogen important increased inhibit interactions intermediate involved Journal known levels liver major mechanism metabolism metabolites metal methyl molecules nature nucleophilic occur organic oxidation oxygen pathway Pharmacology physiological plants polysulfides potential present probably processes properties protection proteins reaction reactive receptor redox reduction reported Research result Reviews ring role Sciences shown similar Society species stability structure studies sulfate sulfide sulfone sulfonium sulfoxide sulfur sulfur compounds synthesis therapeutic thioether thiols thiosulfate tissues toxicity Toxicology urine vitro vivo xenobiotics York