A Life Course Approach to Chronic Disease Epidemiology
The first edition in 1997 of A life course approach to chronic disease epidemiology became a classic text for epidemiological and public health researchers interested in the childhood origins of adult chronic disease. Since then the new field of life course epidemiology has expanded rapidly, attracting the interest not only of academics across the health and social sciences but also policy makers, funding bodies, and the general public. Its purpose is to study how biological and social factors during gestation, childhood, adolescence and earlier adult life independently, cumulatively and interactively influence later life health and disease. Contributors to this fully revised second edition capture the excitement of the developing field and assess the latest evidence regarding sources of risk to health across the life course and across generations. The original chapters on life course influences on cardiovascular disease, diabetes, blood pressure, respiratory disease and cancer have been updated and extended. New chapters on life course influences on obesity, biological ageing and neuropsychiatric disorders have been added. Life course explanations for disease trends and for socioeconomic differentials in disease risk are given more attention in this new edition, reflecting recent developments in the field. The section on policy implications has been expanded, assessing the role of interventions to improve childhood social circumstances, as well as interventions to improve early growth. Emerging new research themes and the theoretical and methodological challenges facing life course epidemiology are highlighted.
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The life course and adult chronic disease an historical perspective with particular reference to coronary heart disease
LIFE COURSE INFLUENCES ON ADULT CHRONIC DISEASE
Preadult influences on cardiovascular disease
Life course approaches to socioeconomic differentials in health
Ischaemic heart disease and cerebrovascular disease mortality trends with special reference to England and Wales are there cohort effects?
Geography and migration with special reference to cardiovascular disease
A life course approach to diabetes
Time trends in cancer incidence and mortality
A life course approach to biological ageing
A life course approach to neuropsychiatric outcomes
BIOLOGICAL AND SOCIAL PROCESSES
Fetal growth and development the role of nutrition and other factors
Socioeconomic pathways between childhood and adult health
IMPLICATIONS FOR POLICY AND FUTURE RESEARCH
Should we intervene to improve fetal and infant growth?
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activity adjustment adolescence adult adulthood approach association Barker behaviour biological birth birthweight blood pressure body born breast cancer cardiovascular disease cause changes Chapter child childhood cohort coronary heart disease countries course Davey Smith death decline determinants diabetes diet early effects England environment environmental Epidemiol epidemiology evidence example exposure factors fetal growth findings function genetic gestational gestational age glucose groups higher human hypothesis hypothyroidism important incidence increased individual infant influences insulin resistance intake intervention Lancet later lead levels long-term lower maternal mean measures mortality myocardial infarction nutrition obesity observed offspring origins outcomes Oxford particularly patterns period physical population position possible potential pregnancy prenatal Press prevalence programming rates recent reduced relationship relative risk risk factors role showed smoking social socioeconomic stroke studies suggested trends twins University weight women young